產(chǎn)品編號(hào) | bs-12774R-Gold |
英文名稱1 | Rabbit Anti-VPS37C/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的液泡蛋白分選蛋白37C抗體 |
別 名 | 5730409F24Rik; AU042646; ESCRT I complex subunit VPS37C; ESCRT-I complex subunit VPS37C; FLJ20847; hVps37C; PML39; RGD1309258; Vacuolar protein sorting 37 homolog C (S. cerevisiae); Vacuolar protein sorting 37C (yeast); Vacuolar protein sorting 37C; Vacuolar protein sorting associated protein 37C; Vacuolar protein sorting-associated protein 37C; VP37C_HUMAN; VPS37C. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 跨膜蛋白 細(xì)胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 39kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human VPS37C |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008] Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. Subcellular Location: Late endosome membrane. Probably associates with membranes. Recruited to the plasma membrane by HIV-1. Similarity: Belongs to the VPS37 family. Contains 1 VPS37 C-terminal domain. Database links: Entrez Gene: 55048 Human Entrez Gene: 107305 Mouse Omim: 610038 Human SwissProt: A5D8V6 Human SwissProt: Q8R105 Mouse Unigene: 523715 Human Unigene: 19091 Mouse Unigene: 12915 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |