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Rabbit Anti-KLRF1/PE-Cy3 Conjugated antibody (bs-16784R-PE-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16784R-PE-Cy3
英文名稱 Rabbit Anti-KLRF1/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的殺傷細胞凝集素樣受體F1抗體
別    名 Activating coreceptor NKp80; C type lectin domain family 5 member C; CLEC5C; KLRF1_HUMAN; killer cell lectin like receptor F1; Killer cell lectin like receptor subfamily F member 1; KLRF 1; Lectin like receptor F1; MGC119907; MGC119908; MGC119909; ML; NKp80.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  自然殺傷細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KLRF1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]

Function:
KLRF1 is involved in the natural killer mediated cytolysis of PHA-induced lymphoblasts.

Subunit:
Homodimer.

Subcellular Location:
Membrane; Single-pass type II membrane protein

Tissue Specificity:
Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 51348 Human

Omim: 605029 Human

SwissProt: Q9NZS2 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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