亚洲中文字幕特级毛片-亚洲制服丝袜中文字幕-亚洲制服丝袜在线观看-亚洲制服欧美自拍另类-免费一级黄色-免费一级国产生活片

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
99久久er这里只有精品18,被按摩的人妻中文字幕,国产午夜福利短视频
Rabbit Anti-phospho-CK18(Ser60)/HRP Conjugated antibody (bs-5405R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@www.chomd.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.chomd.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5405R-HRP
英文名稱1 Rabbit Anti-phospho-CK18(Ser60)/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的磷酸化細(xì)胞角蛋白18抗體
別    名 Cytokeratin 18 (phospho S60); p-Cytokeratin 18 (phospho S60); Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46; Cell proliferation-inducing gene 46 protein; CK 18; CK-18; CK18; CYK 18; CYK18; Cytokeratin 18; Cytokeratin endo B; Cytokeratin-18; Cytokeratin18; K 18; K18; K1C18_HUMAN; Keratin 18; Keratin D; Keratin type I cytoskeletal 18; keratin, type I cytoskeletal 18; Keratin-18; Keratin18; Kerd; KRT18.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  信號轉(zhuǎn)導(dǎo)  細(xì)胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat, 
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human CK18 around the phosphorylation site of Ser60 [MG(p-S)GG]
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Function:
When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Subunit:
Heterotetramer of two type I and two type II keratins. KRT18 associates with KRT8. Interacts with the thrombin-antithrombin complex (By similarity). Interacts with PNN, HCV core protein and mutated CFTR. Interacts with YWHAE, YWHAH and YWHAZ only when phosphorylated. Interacts with DNAJB6, TCHP and TRADD.

Subcellular Location:
Cytoplasm, perinuclear region. Nucleus, nucleolus.

Tissue Specificity:
Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.

Post-translational modifications:
Phosphorylation increases by IL-6.
Proteolytically cleaved by caspases during epithelial cell apoptosis. Cleavage occurs at Asp-231 by either caspase-3, caspas-6 or caspase-7.
O-glycosylated at multiple sites; glycans consist of single N-acetylglucosamine residue.

DISEASE:
Defects in KRT18 are a cause of cirrhosis (CIRRH) [MIM:215600].

Similarity:
Belongs to the intermediate filament family.

Database links:

Entrez Gene: 506480 Cow

Entrez Gene: 3875 Human

Entrez Gene: 16668 Mouse

Entrez Gene: 294853 Rat

Omim: 148070 Human

SwissProt: P05783 Human

SwissProt: P05784 Mouse

SwissProt: Q5BJY9 Rat

Unigene: 406013 Human

Unigene: 22479 Mouse

Unigene: 103924 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

結(jié)構(gòu)蛋白(Structural Proteins)常用于腫瘤細(xì)胞的分化、增殖及轉(zhuǎn)移方面的研究。
版權(quán)所有 2004-2026 www.www.chomd.com.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 中文字幕久久精品无码高清| 午夜天堂一区人妻美女永久免费 | 96精品久久久无码午| 亚洲综合久久综合激情久久久 | 国产无遮挡成人免费视频网站的软件 | 伊人久久精品一区二区 黑牛影视 伊人久久精品一区二区区三区 | 丰满少妇又爽又紧又丰满在线观看精品国产一区二区 | 97久久久久人妻精品专区一97久久久 | 99精品偷自拍 | 日韩| 亚洲AV无码乱码国产精品蜜芽| 久久996热精品re | 粉嫩AV四季AV绯色AV第一区| 亚洲视频高清无码国产传媒| 久久国产亚洲高清观看5388,国产日韩欧美二区_ | 国产偷久久久精品专区!| 亚洲一线产区二线产区精华黄色视频 | 中文字幕在线视频网站99在 | 无码人妻一区二区三区乐博AV| 国产主播在线一区尤物| 亚洲人成网站色情久久久久久| 精品九九人人做人人爱,久久青草成人 | 亚洲精品专区在线观看污| 久久99精品久久久久久清纯直懂色| 91精品国产乱码久久久久久夜夜嗨 | 岛国无码在线不卡av| 婷婷免费视频| av无码在线观看一区二区麻豆| 三上悠亚日韩在线一区观看| 99人中文字幕亚洲区三不卡| 免费人妻精品一区二区三区小宝探花 | 亚洲熟妇Hp视频| 国产一二三区在线观看thp| 亚洲AV美国人与鲁| 波多野结衣毛片| 久久综合日韩欧美| 亚洲另类少妇激情白浊黑紫| 国产草莓视频在线观看免费|国产 国产超碰人人做人人爱,最新亚洲AV日韩AV二 | 中文字幕中文字幕在线观看伊人 | 国产私拍福利精品视频推出87| 羞羞视频在线观看入口污导航一区视频 | 亚欧成人中文字幕一区欧洲一区在线观看_精 |