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Rabbit Anti-AQP1/Gold Conjugated antibody (bs-1506R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-1506R-Gold
英文名稱1 Rabbit Anti-AQP1/Gold Conjugated antibody
中文名稱 膠體金標記的水通道蛋白1抗體
別    名 AQP 1; AQP-1; AQP1_HUMAN; Aquaporin-1; Aquaporin-CHIP; Channel like integral membrane protein 28 kDa; MGC26324; Water channel protein CHIP 29; AQP CHIP; AQP1; Aquaporin CHIP; Aquaporin1; Aquaporin 1; Channel forming integral protein 28kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; Urine water channel; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  信號轉導  通道蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AQP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

Function:
Forms a water-specific channel that provides the plasmamembranes of red cells and kidney proximal tubules with highpermeability to water, thereby permitting water to move in thedirection of an osmotic gradient.

Subunit:
Homotetramer. Interacts with EPHB2; involved in endolymphproduction in the inner ear (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.

Similarity:
Belongs to the MIP/aquaporin (TC 1.A.8) family.

Database links:

Entrez Gene: 358 Human

Entrez Gene: 11826 Mouse

Entrez Gene: 25240 Rat

Entrez Gene: 442999 Sheep

Entrez Gene: 282653 Cow

Entrez Gene: 403732 Dog

Omim: 107776 Human

SwissProt: P47865 Cow

SwissProt: Q9N2J4 Dog

SwissProt: P29972 Human

SwissProt: Q02013 Mouse

SwissProt: P29975 Rat

SwissProt: P56401 Sheep

Unigene: 76152 Human

Unigene: 18625 Mouse

Unigene: 1618 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

通道蛋白(Channel Protein)
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