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Mouse Anti-phospho-Tau (Thr231)  antibody (bsm-25325M)  
~~~促銷代碼KT202411~~~
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產品編號 bsm-25325M
英文名稱 Mouse Anti-phospho-Tau (Thr231)  antibody
中文名稱 磷酸化微管相關蛋白單克隆抗體
別    名 Tau (phospho T231); p-Tau (phospho T231); Tau(Phospho-Thr231); MAPT(phospho T231); p-Tau(Thr231); MAPT; Microtuble-associted protein Tau; AI413597; AW045860; DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FLJ31424; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PHF-tau; PPND; pTau; RNPTAU; Tauopathy and respiratory failure, included; TAU_HUMAN.  
產品類型 磷酸化抗體 
研究領域 細胞生物  免疫學  神經生物學  轉錄調節因子  
抗體來源 Mouse
克隆類型 Monoclonal
交叉反應 Human
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human phospho-Tau (Thr231) 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M PBS (pH7.4).
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

SWISS:
P10636

Gene ID:
4137

Database links:

Entrez Gene: 281296 Cow

Entrez Gene: 4137 Human

Entrez Gene: 17762 Mouse

Entrez Gene: 29477 Rat

Omim: 157140 Human

SwissProt: P29172 Cow

SwissProt: P10636 Human

SwissProt: P10637 Mouse

SwissProt: P19332 Rat

Unigene: 101174 Human

Unigene: 1287 Mouse

Unigene: 2455 Rat




產品圖片
Sample: Lane 1: Human SH-SY5Y cell lysates Primary: Anti-phospho-Tau (Thr231) (bsm-25325M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 46/79 kDa Observed band size: 50 kDa
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