產(chǎn)品編號 | C03-15003 |
英文名稱 | Mouse IgM / PerCP Isotype Control |
中文名稱 | PerCP標(biāo)記小鼠IgM(同型對照) |
別 名 | Mouse Immunoglobulin M/PerCP Isotype Control; PerCP mouse IgM; mouse IgM/PerCP; mouse IgM PerCP conjugated; 熒光素PerCP標(biāo)記小鼠IgM同型對照 |
性 狀 | Liquid |
保存條件 | Store at 2-8℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |