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Rabbit Anti-PLA2G2A  antibody (bs-20533R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-20533R
英文名稱 Rabbit Anti-PLA2G2A  antibody
中文名稱 分泌型磷脂酶A2抗體
別    名 PA2GA_HUMAN; Phospholipase A2, membrane associated; EC:3.1.1.4; GIIC sPLA2; Group IIA phospholipase A2; Non-pancreatic secretory phospholipase A2 (NPS-PLA2); Phosphatidylcholine 2-acylhydrolase 2A; PLA2B; PLA2L; RASF-A; phospholipase A2 group IIA; MOM1; PLA2; PLA2S; PLAS1; sPLA2;  
研究領域 細胞生物  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14kDa
細胞定位 細胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLA2G2A: 51-100/144 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]

Function:
Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Subcellular Location:
Membrane.

Similarity:
Belongs to the phospholipase A2 family.

SWISS:
P14555

Gene ID:
5320

Database links:

Entrez Gene: 5320 Human

Entrez Gene: 18780 Mouse

Entrez Gene: 29692 Rat

Omim: 172411 Human

SwissProt: P14555 Human

SwissProt: P31482 Mouse

SwissProt: P14423 Rat

Unigene: 466804 Human

Unigene: 4675 Mouse

Unigene: 11346 Rat



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