| 產品編號 | bs-2792R |
| 英文名稱 | Rabbit Anti-CRHR2 antibody |
| 中文名稱 | 促腎上腺皮質釋放激素受體2抗體 |
| 別 名 | Corticotropin releasing hormone receptor 2; Corticotropin Releasing Factor Receptor 2; Corticotropin-releasing hormone receptor 2; Corticotropin-releasing factor receptor 2; CRF 2; CRF 2R; CRF R2; CRF2; CRF2R; CRFR 2; CRFR2; CRH 2R; CRH R2; CRH2R; CRHR 2; CRHR2; CRHRⅡ. |
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Specific References (1) | bs-2792R has been referenced in 1 publications.
[IF=3.671] Fan,et al.Antitumor activity and underlying mechanism of Sargassum fusiforme polysaccharides in CNE-bearing mice.(2018) International Journal of Biological Macromolecules. 112:516-522. Other ; Mouse.
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| 研究領域 | 免疫學 神經生物學 G蛋白偶聯受體 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
| 產品應用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CRHR2: 51-150/411 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011] Function: This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit: Interacts (via N-terminal extracellular domain) with CRF, UCN, UCN2 and UCN3. Has highest affinity for UCN, and considerably lower affinity for CRF, UNC2 and UCN3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2 family. SWISS: Q13324 Gene ID: 1395 Database links: Entrez Gene: 1395 Human Entrez Gene: 12922 Mouse Omim: 602034 Human SwissProt: Q13324 Human SwissProt: Q60748 Mouse Unigene: 546246 Human Unigene: 236081 Mouse Unigene: 10023 Rat |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
