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Rabbit Anti-SMPD4/AP Conjugated antibody (bs-12641R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12641R-AP
英文名稱1 Rabbit Anti-SMPD4/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的鞘磷脂磷酸二酯酶4抗體
別    名 EC 3.1.4.12; EC=3.1.4.123; FLJ20297; FLJ20756; KIAA1418; NET 13; NET13; Neutral sphingomyelinase 3; Neutral sphingomyelinase III; NSMA3_HUMAN; nSMase 3; nSMase-3; nSMase3; OTTHUMP00000162391; OTTHUMP00000190862; SKNY protein; smpd4; Sphingomyelin phosphodiesterase 4; Sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase 3).  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 93kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SMPD4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Sphingomyelinases (EC 3.1.4.12), such as SMPD4, catalyze the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (Krut et al., 2006 [PubMed 16517606]).[supplied by OMIM, Mar 2008]

Function:
Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide.

Subunit:
Associates with spliceosomes. Associates with U4/U5/U6 tri-snRNP and with U2 snRNP.

Subcellular Location:
Endoplasmic reticulum membrane. Golgi apparatus membrane.

Tissue Specificity:
Widely expressed, with highest levels in heart and skeletal muscle.

Similarity:
Belongs to the SMN family. Contains 1 Tudor domain.

Database links:

Entrez Gene: 55627 Human

Entrez Gene: 77626 Mouse

Entrez Gene: 303790 Rat

Omim: 610457 Human

SwissProt: Q9NXE4 Human

SwissProt: Q6ZPR5 Mouse

Unigene: 516450 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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