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Rabbit Anti-PLS1/BF488 Conjugated antibody (bs-12735R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12735R-BF488
英文名稱1 Rabbit Anti-PLS1/BF488 Conjugated antibody
中文名稱 BF488標記的腸道特異性凝血酶PLS1抗體
別    名 Fimbrin; I Fimbrin; I Plastin; Intestine specific plastin; Plastin 1 (I isoform); Plastin 1; Plastin1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  結合蛋白  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLS1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010]

Function:
Actin-bundling protein in the absence of calcium.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
In small intestine, colon, and kidney; relatively lower levels of expression are detected in the lung and stomach.

Post-translational modifications:
Phosphorylated.

Similarity:
Contains 2 actin-binding domains.
Contains 4 CH (calponin-homology) domains.
Contains 2 EF-hand domains.

Database links:

Entrez Gene: 5357 Human

Entrez Gene: 102502 Mouse

Entrez Gene: 315926 Rat

Omim: 602734 Human

SwissProt: Q14651 Human

SwissProt: Q3V0K9 Mouse

Unigene: 203637 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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