產品編號 | bs-20099R-APC |
英文名稱1 | Rabbit Anti-ARL8B/APC Conjugated antibody |
中文名稱 | APC標記的ADP核糖基化樣因子8B抗體 |
別 名 | ADP ribosylation factor like 10C; ADP-ribosylation factor-like protein 10C; ADP-ribosylation factor-like protein 8B; ARL10C; ARL8B; ARL8B_HUMAN; FLJ10702; Gie1; Novel small G protein indispensable for equal chromosome segregation 1. |
規格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 細胞生物 細胞周期蛋白 細胞分化 表觀遺傳學 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | |
產品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ARL8B |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產品介紹 |
background: ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of Cholera Toxin. ARF’s are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL8B (ADP-ribosylation factor-like protein 8B), also known as ARL10C or GIE1, is a 186 amino acid protein that localizes to the late endosome membrane and belongs to the ARL family of ARF-like GTPase proteins. Expressed ubiquitously, ARL8A interacts with Tubulin and is thought to play a role in lysosome motility, as well as in chromosomal segregation. The gene encoding ARL8B maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Function: May play a role in lysosome motility (PubMed:16537643). May play a role in chromosome segregation (PubMed:15331635). Subunit: Interacts with tubulin. Subcellular Location: Late endosome membrane. Lysosome membrane. Cytoplasm, cytoskeleton, spindle. Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the small GTPase superfamily. Arf family. Database links: Entrez Gene: 55207 Human SwissProt: Q9NVJ2 Human Unigene: 250009 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |