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Rabbit Anti-PPP1R1C/Gold Conjugated antibody (bs-19991R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19991R-Gold
英文名稱1 Rabbit Anti-PPP1R1C/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的蛋白磷酸酶1調(diào)節(jié)亞基1c抗體
別    名 Inhibitor 5 of protein phosphatase 1; IPP5; PP1 inhibitor protein 5; Ppp1r1c; PPR1C_HUMAN; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase 1 regulatory subunit 1C; protein phosphatase 1, regulatory (inhibitor) subunit 1C.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PPP1R1C
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Function:
Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level).

Post-translational modifications:
Phosphorylation at Ser-56 favors interaction with CALM1.
Isoform 1 is methylated by CARM1 in immature thymocytes.

Similarity:
Contains 1 R3H domain.

Database links:

Entrez Gene: 10777 Human

Entrez Gene: 74100 Mouse

Entrez Gene: 363153 Rat

Omim: 605488 Human

SwissProt: Q9UBL0 Human

SwissProt: Q9DCB4 Mouse

Unigene: 475902 Human

Unigene: 713605 Human

Unigene: 297444 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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