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Rabbit Anti-RGS3/AP Conjugated antibody (bs-19861R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19861R-AP
英文名稱1 Rabbit Anti-RGS3/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的G蛋白信號(hào)轉(zhuǎn)導(dǎo)調(diào)節(jié)因子3抗體
別    名 C2PA; FLJ20370; FLJ31516; FLJ90496; PDZ RGS 3; PDZ RGS3; Regulator of G protein signaling 3; Regulator of G protein signalling 3; Regulator of G-protein signaling 3; RGP 3; RGP3; RGS 3; RGS3; RGS3_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 132kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RGS3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.

Subcellular Location:
Cytoplasm. Nucleus. Cell membrane. Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear.

Post-translational modifications:
Phosphorylated by cyclic GMP-dependent protein kinase. ISGylated.

Similarity:
Contains 1 C2 domain.
Contains 1 PDZ (DHR) domain.
Contains 1 RGS domain.

Database links:

Entrez Gene: 5998 Human

Entrez Gene: 50780 Mouse

Entrez Gene: 54293 Rat

Omim: 602189 Human

SwissProt: P49796 Human

SwissProt: Q9DC04 Mouse

SwissProt: P49797 Rat

Unigene: 494875 Human

Unigene: 286753 Mouse

Unigene: 53900 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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