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Rabbit Anti-ZDHHC15/BF350 Conjugated antibody (bs-18478R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18478R-BF350
英文名稱1 Rabbit Anti-ZDHHC15/BF350 Conjugated antibody
中文名稱 BF350標記的ZDHHC15蛋白抗體
別    名 DHHC-15; Palmitoyltransferase ZDHHC15; UNQ1969/PRO4501; ZDH15_HUMAN; Zdhhc15; Zinc finger DHHC domain-containing protein 15.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  細胞生物  免疫學  神經生物學  轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZDHHC15
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Function:
Palmitoyltransferase specific for GAP43 and DLG4/PSD95.

Subcellular Location:
Membrane.

Post-translational modifications:
Autopalmitoylated.

DISEASE:
Defects in ZDHHC15 are the cause of mental retardation X-linked type 91 (MRX91) [MIM:300577]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.

Similarity:
Belongs to the DHHC palmitoyltransferase family.
Contains 1 DHHC-type zinc finger.

Database links:

Entrez Gene: 158866 Human

Omim: 300576 Human

SwissProt: Q96MV8 Human

Unigene: 253211 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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