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Rabbit Anti-MARS2/BF488 Conjugated antibody (bs-18683R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-18683R-BF488
英文名稱1 Rabbit Anti-MARS2/BF488 Conjugated antibody
中文名稱 BF488標記的甲硫氨酸轉運RNA合成酶2抗體
別    名 mars2; Methionine tRNA ligase 2; Methionine tRNA ligase 2 mitochondrial; Methionine tRNA ligase; Methionine tRNA synthetase 2; Methionine--tRNA ligase; Methionyl tRNA synthetase 2 mitochondrial; Methionyl tRNA synthetase mitochondrial; Methionyl-tRNA synthetase 2; MetRS; mitochondrial; Mitochondrial methionine tRNA ligase; Mitochondrial methionyl tRNA synthetase; Mitochondrial methionyl-tRNA synthetase; MtMetRS; SYMM_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  轉運蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Dog, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MARS2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014]

DISEASE:
Spastic ataxia 3, autosomal recessive (SPAX3) [MIM:611390]: A neurologic disorder characterized by cerebellar ataxia, ataxic gait, spasticity, and hyperreflexia. Other variable features include dysarthria, dysmetria, mild cognitive impairment, urinary urgency and dystonic positioning. Note: The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the class-I aminoacyl-tRNA synthetase family.

Database links:

Entrez Gene: 92935 Human

Omim: 609728 Human

SwissProt: Q96GW9 Human

Unigene: 116602 Human

Unigene: 744330 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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