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Rabbit Anti-MRGPRX4/PE-Cy5 Conjugated antibody (bs-17761R-PE-Cy5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17761R-PE-Cy5
英文名稱1 Rabbit Anti-MRGPRX4/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標記的MRGPRX4蛋白抗體
別    名 G protein coupled receptor MRGX4; G protein coupled receptor SNSR5; G protein coupled receptor SNSR6; GPCR; Mas related G protein coupled receptor member X4; Mas related G protein coupled-receptor family, member X4; MAS related GPR, member X4; Mas-related G-protein coupled receptor member X4; MGC129753; MGC129754; MRGPRX4; MRGX4; MRGX4_HUMAN; Sensory neuron specific G protein coupled receptor 5/6; Sensory neuron-specific G-protein coupled receptor 5/6; SNSR5; SNSR6.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MRGPRX4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產品介紹 background:
Mas-related G protein-coupled receptor member X1 (MRGX) is a sensory neuron-specific G protein-coupled receptor that is involved in the function of nociceptive neurons. This integral membrane protein may also regulate nociceptor development and/or the sensation or modulation of pain. There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G?q- and G?i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G?q-regulated pathways. G?q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons.

Function:
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

Database links:

Entrez Gene: 117196 Human

Omim: 607230 Human

SwissProt: Q96LA9 Human

Unigene: 632138 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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