產(chǎn)品編號 | bs-16880R-AP |
英文名稱1 | Rabbit Anti-L3MBTL2/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標(biāo)記的致死因子惡性腦瘤樣蛋白2抗體 |
別 名 | 3bt like 2 protein; 3bt like protein; DKFZP761I141; H-l(3)mbt-like protein 2; H-l(3)mbt-like protein; Hl; Hl(3)mbt like protein; Hl(3)mbtl; L; l(3)mbt like 2 (Drosophila); l(3)mbt like 2; L(3)mbt-like 2 protein; L(3)mbt-like protein 2; L3MBTL2; Lethal; Lethal(3)malignant brain tumor-like 2 protein; Lethal(3)malignant brain tumor-like protein 2; LMBL2_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, Rat, (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 79kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human L3MBTL2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. Function: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or'Lys-27'. Subunit: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR,BAT8 and YAF2. Subcellular Location: Nucleus. Similarity: Contains 1 FCS-type zinc finger. Contains 4 MBT repeats. Database links: Entrez Gene: 83746 Human Entrez Gene: 214669 Mouse Omim: 611865 Human SwissProt: Q969R5 Human SwissProt: P59178 Mouse Unigene: 517641 Human Unigene: 280768 Mouse Unigene: 137566 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |