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Rabbit Anti-FRZB/FRP-3/Gold Conjugated antibody (bs-16185R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-16185R-Gold
英文名稱1 Rabbit Anti-FRZB/FRP-3/Gold Conjugated antibody
中文名稱 膠體金標記的FRZB蛋白抗體
別    名 FIZ; FRE; Frezzled; Fritz; Frizzled-related protein 1; FRP; FrzB 1; FRZB; MYOZ3_HUMAN; FRZB1; OTTMUSP00000014350; RP23-33L19.1; Secreted frizzled related protein 3 [Precursor]; Secreted frizzled related sequence protein 3; sFRP 3; SFRP.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  信號轉導  干細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FRZB/FRP-3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. [provided by RefSeq, Apr 2010]

Function:
SFRP3/FRZB appears to be involved in limb skeletogenesis by regulating chondrocyte maturation and long bone development. Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. Antagonist of Wnt8 signaling.

Subcellular Location:
Secreted

Tissue Specificity:
Expressed specifically in skeletal muscle. Not detected in heart.

Similarity:
Belongs to the myozenin family.

Database links:

Entrez Gene: 2487 Human

Omim: 605083 Human

SwissProt: Q92765 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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