| 產(chǎn)品編號(hào) | bs-16625R-Gold |
| 英文名稱1 | Rabbit Anti-IMPACT/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的IMPACT蛋白抗體 |
| 別 名 | IMPACT; Impact homolog (mouse); Impact homolog; impact RWD domain protein; IMPCT_HUMAN; Imprinted and ancient gene protein homolog; MGC33718; Protein IMPACT; RWD domain containing 5; RWDD5. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, Dog, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IMPACT |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. Function: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity). Subunit: Interacts with GCN1/GCN1L1 (By similarity). Subcellular Location: Cytoplasm (By similarity). Note=May be associated with polysomes (By similarity). Tissue Specificity: Widely expressed. Expressed at high level in brain. Similarity: Belongs to the IMPACT family. Contains 1 RWD domain. Database links: Entrez Gene: 55364 Human Entrez Gene: 100009333 Rabbit SwissProt: Q9P2X3 Human SwissProt: Q5GFD8 Rabbit Unigene: 515317 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
