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Rabbit Anti-DOPEY1/APC Conjugated antibody (bs-14409R-APC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14409R-APC
英文名稱1 Rabbit Anti-DOPEY1/APC Conjugated antibody
中文名稱 APC標記的遲鈍蛋白家族1抗體
別    名 Dopey-1; DOP1; DOP1_HUMAN; Dopey family member 1; DOPEY1; KIAA1117; Protein dopey 1; Protein dopey-1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 277kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DOPEY1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Dopey-1 is a 2,465 amino acid protein that is thought to be involved in protein trafficking between the late golgi and early endosomes and may be involved in neurological alternations and mental retardation associated with Down syndrome. The gene encoding Dopey-1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

Function:
May be involved in protein traffic between late Golgi and early endosomes.

Similarity:
Belongs to the dopey family.

Database links:

Entrez Gene: 23033 Human

Entrez Gene: 320615 Mouse

SwissProt: Q5JWR5 Human

SwissProt: Q8BL99 Mouse

Unigene: 520246 Human

Unigene: 708998 Human

Unigene: 245500 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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