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Rabbit Anti-NPFF2/RBITC Conjugated antibody (bs-19328R-RBITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19328R-RBITC
英文名稱1 Rabbit Anti-NPFF2/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的神經肽G蛋白偶聯受體抗體
別    名 G protein coupled receptor 74; G protein coupled receptor HLWAR 77; G protein coupled receptor HLWAR77; G-protein coupled receptor 74; G-protein coupled receptor HLWAR77; GPR 74; GPR74; HG31; HLWAR77; Neuropeptide FF receptor 2; Neuropeptide FF2; Neuropeptide G protein coupled receptor; Neuropeptide G-protein coupled receptor; NPFF 2; NPFF R2; NPFF2_HUMAN; NPFFR 2; Npffr2; NPGPR.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse NPFF2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Function:
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Isoform 1 is abundant in placenta. Relatively highly expressed in thymus, testis, and small intestine. Expressed at low levels in several tissues including spleen, prostate, brain, heart, ovary, colon, kidney, lung, liver and pancreas and not expressed in skeletal muscle and leukocytes. Isoform 2 expression is highest in placenta (but at relatively low level compared to isoform 1). Very low level of expression in numerous tissues including adipose tissue and many brain regions. Isoform 3 is expressed in brain and heart and, at lower levels, in kidney, liver, lung and pancreas.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 10886 Human

Entrez Gene: 530560 Cow

Entrez Gene: 100686684 Dog

Entrez Gene: 100659439 Elephant

Entrez Gene: 101125905 Gorilla

Entrez Gene: 100393976 Marmoset (common)

Entrez Gene: 100524634 Pig

Entrez Gene: 100347167 Rabbit

Omim: 607449 Human

SwissProt: Q9Y5X5 Human

Unigene: 99231 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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