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Rabbit Anti-NEK10/Gold Conjugated antibody (bs-19194R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-19194R-Gold
英文名稱1 Rabbit Anti-NEK10/Gold Conjugated antibody
中文名稱 膠體金標記的絲氨酸/蘇氨酸蛋白激酶Nek10抗體
別    名 FLJ32685; Never in mitosis A related kinase 10; NIMA (never in mitosis gene a) related kinase 10; NimA related protein kinase 10; Serine/threonine protein kinase Nek10. NEK10_HUMAN   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 133kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NEK10
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Nek10 is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.
Predicted molecular weight: 55 kDa for Isoform 5 (and 133 kDa for Isoform 1).

Function:
NEK10 belongs to the protein kinase superfamily; Ser/Thr protein kinase family; NIMA subfamily.

Similarity:
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Contains 1 ARM repeat.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 152110 Human

Entrez Gene: 238944 Mouse

SwissProt: Q6ZWH5 Human

SwissProt: Q3UGM2 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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