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Rabbit Anti-NCKAP5/BF555 Conjugated antibody (bs-13693R-BF555)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13693R-BF555
英文名稱1 Rabbit Anti-NCKAP5/BF555 Conjugated antibody
中文名稱 BF555標記的NCKAP5蛋白抗體
別    名 ERIH1; ERIH2; NAP-5; NAP5; Nck-associated protein 5; NCKAP5; NCKP5_HUMAN; Peripheral clock protein.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 信號轉導  跨膜蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 208kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NCKAP5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產品介紹 background:
NAP5 (Nck-associated protein 5), also known as peripheral clock protein, NCKAP5 or ERIH, is a 1,909 amino acid nuclear protein that is expressed in fetal and adult brain, leukocytes and fetal fibroblasts. Containing pro-rich sequences, NAP5 interacts with the adapter protein Nck via the SH3-containing region. Existing as four alternatively spliced isoforms, the gene encoding NAP5 maps to human chromosome 2q21.2 and mouse chromosome 1 E3. Human chromosome 2, the second largest human chromosome, consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene present on chromosome 2. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome, is due to mutations in the ALMS1 gene.

Subunit:
Interacts with the SH3-containing region of the adapter protein NCK.

Tissue Specificity:
Expressed in fetal and adult brain, leukocytes and fetal fibroblasts.

Database links:

Entrez Gene: 344148 Human

SwissProt: O14513 Human

Unigene: 537329 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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