| 產(chǎn)品編號 | bs-7344R-Gold |
| 英文名稱1 | Rabbit Anti-OAS3/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的2'-5'-寡腺苷酸合成酶3抗體 |
| 別 名 | (2-5'')oligo(A) synthase 3; 2 5' oligo(A) synthetase 3; 2 5'LIGO; 2 5A synthetase 3; 2''-5''-oligoadenylate synthase 3; 2-5A synthase 3; MGC133260; OAS3 2' 5' oligoadenylate synthetase 3, 100kDa; OAS3; OAS3_HUMAN; p100; p100 OAS; p100OAS. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細胞生物 免疫學(xué) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, (predicted: Rat, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 121kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human OAS3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2 Function: May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2',5'-oligoadenylate molecules. GTP can be an alternative substrate. Tissue Specificity: Present at high level in placenta trophoblast. Similarity: Belongs to the 2-5A synthase family. Database links: Entrez Gene: 4940 Human Omim: 603351 Human SwissProt: Q9Y6K5 Human Unigene: 528634 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
