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Rabbit Anti-PTCHD2/Gold Conjugated antibody (bs-12324R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-12324R-Gold
英文名稱1 Rabbit Anti-PTCHD2/Gold Conjugated antibody
中文名稱 膠體金標記的多通道膜蛋白PTCHD2抗體
別    名 DISP3; Dispatched, drosophila, homolog of, 3; G630052C06Rik; hCG_24779; KIAA1337; Patched domain-containing protein 2; Protein dispatched homolog 3; Ptchd2; PTHD2_HUMAN; RGD1305820; RND-type protein RNDEu-2; RNDEu-2; patched domain containing 2; RP23-157B15.1; PTCHD2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  心血管  細胞生物  神經生物學  信號轉導  通道蛋白  新陳代謝  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 153 kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human PTCHD2/DISP3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:
Expressed in brain and testis.

Similarity:
Belongs to the patched family.
Contains 1 SSD (sterol-sensing) domain.

Database links:

Entrez Gene: 57540 Human

Omim: 611251 Human

SwissProt: Q9P2K9 Human

Unigene: 202355 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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