產(chǎn)品編號 | bs-12129R-Gold |
英文名稱1 | Rabbit Anti-ACCN4/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的腦鈉通道蛋白4抗體 |
別 名 | Accn4; ACCN4_HUMAN; Acid sensing (proton gated) ion channel family member 4; Acid sensing ion channel 4; Acid-sensing ion channel 4; Amiloride sensitive cation channel 4; Amiloride sensitive cation channel 4 pituitary; Amiloride sensitive cation channel family member 4 pituitary; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4; ASIC4; BNAC4; Brain sodium channel 4; pituitary. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 70kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ACCN4/ASIC4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]. Function: Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. Subunit: Homotrimer or heterotrimer with other ASIC proteins. Subcellular Location: .Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. Similarity: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ACCN4 subfamily. Database links: Entrez Gene: 55515 Human Entrez Gene: 241118 Mouse Omim: 606715 Human SwissProt: Q96FT7 Human SwissProt: Q7TNS7 Mouse Unigene: 87469 Human Unigene: 110790 Mouse Unigene: 44831 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |