產(chǎn)品編號 | bs-14008R-Gold |
英文名稱1 | Rabbit Anti-COX6A2/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的細(xì)胞色素C氧化酶蛋白6A2抗體 |
別 名 | COX VIa M; COX6AH; COXVIAH; Cytochrome c oxidase polypeptide VIa heart; Cytochrome c oxidase subunit 6A2 mitochondrial; Cytochrome c oxidase subunit VIA muscle; Cytochrome c oxidase subunit VIa polypeptide 2; MS411. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 新陳代謝 線粒體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 9.6kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human COX6A2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq, Jul 2008] Function: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. COX is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. COX6A2 is polypeptide 2 of subunit VIa, and is present only in striated muscles. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. Subcellular Location: Mitochondrion inner membrane Tissue Specificity: Expressed specifically in heart and muscle. Similarity: Belongs to the cytochrome c oxidase subunit 6A family. Database links: Entrez Gene: 1339 Human Entrez Gene: 12862 Mouse Omim: 602009 Human SwissProt: Q02221 Human SwissProt: P43023 Mouse Unigene: 250760 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |