產(chǎn)品編號(hào) | bs-5823R-Gold |
英文名稱1 | Rabbit Anti-K Cadherin/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的鈣粘蛋白6抗體 |
別 名 | Cadherin 6; Cadherin6; Cadherin-6; Cadherin 6 type 2; Cadherin fetal kidney; Cadherin6; CDH 6; CDH6; KCAD; Kidney cadherin; CADH6_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Rat, Cow, Horse, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 82kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human K Cadherin |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: K Cadherin (Cadherin 6) is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells. K Cadherin is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. It is also expressed in certain liver and kidney carcinomas. Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. Similarity: Contains 5 cadherin domains. Database links: Entrez Gene: 1004 Human Entrez Gene: 12563 Mouse Omim: 603007 Human SwissProt: P55285 Human SwissProt: P97326 Mouse Unigene: 124776 Human Unigene: 171054 Human Unigene: 57048 Mouse Unigene: 10390 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |