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Rabbit Anti-Substance P/PE-Cy5.5 Conjugated antibody (bs-0065R-PE-Cy5.5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-0065R-PE-Cy5.5
英文名稱1 Rabbit Anti-Substance P/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的P物質抗體
別    名 Hs.2563; Neurokinin 1; Neurokinin 2; Neurokinin A; Neurokinin alpha; Neuromedin L; Neuropeptide gamma; NKA; NKNA; PPT; Protachykinin 1 precursor; Substance K; Substance P; TAC1; TAC2; Tachykinin 1; Tachykinin 2; Tachykinin precursor 1; Tachykinin1; TACI; TKN1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, G)
產品應用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 1.4/13kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Substance P
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

Subcellular Location:
Secreted.

Similarity:
Belongs to the tachykinin family.

Database links:

Entrez Gene: 6863 Human

Entrez Gene: 21333 Mouse

Entrez Gene: 24806 Rat

Omim: 162320 Human

SwissProt: P20366 Human

SwissProt: P41539 Mouse

SwissProt: P06767 Rat

Unigene: 2563 Human

UniProtKB/Swiss-Prot: P20366.1



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

P物質(Substance P)是腦組織及消化道中發現的一種神經遞質肽。由130個氨基酸殘基組成,胃腸道中肌肉收縮的有力促進劑,亦為強血管擴張劑。
SP是一種腦腸肽,亦是最早發現的一種神經肽,屬于速激肽家族成員,它廣泛分布于中樞及外周神經系統,作為一種神經遞質或調質參與疼痛、免疫、心血管等多種生理功能的調節。SP與其它的遞質或調質類似,能作用于多種類型的受體,速激肽家族有NK1、NK2、NK3三種受體,都能與SP結合,其中NK1與SP的結合能力最強而被稱為SP受體。
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