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Rabbit Anti-Lysozyme/BF350 Conjugated antibody (bs-0816R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-0816R-BF350
英文名稱1 Rabbit Anti-Lysozyme/BF350 Conjugated antibody
中文名稱 BF350標記的溶菌酶抗體
別    名 1 4 beta n acetylmuramidase c; 14 beta N acetylmuramidase; 14 beta N acetylmuramidase C; EC 3.2.1.17; lysosyme; Lysozyme C; Lysozyme C precursor; Lyz; LZM; Muramidase.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  激酶和磷酸酶  合成與降解  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Rabbit, Sheep, Monkey, Cat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Full length native Lysozyme
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Lysozyme catalyzes the hydrolysis of certain mucopolysaccharides of bacterial cell walls. Specifically, it catalyzes the hydrolysis of the bacterial cell wall beta glycosidic linkages between N acetylmuramic acid and N acetylglucosamine. It is found in spleen, lung, kidney, white blood cells, plasma, saliva, milk, and tears.

Subcellular Location:
Secreted.

DISEASE:
Defects in LYZ are a cause of amyloidosis type 8 (AMYL8) [MIM:105200]; also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash.

Similarity:
Belongs to the glycosyl hydrolase 22 family.

Database links:

Entrez Gene: 4069 Human

Entrez Gene: 17105 Mouse

Entrez Gene: 17110 Mouse

Omim: 153450 Human

SwissProt: P61626 Human

SwissProt: P08905 Mouse

Unigene: 524579 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

溶菌酶(lysozyme )又稱細胞壁質酶(muramidase)或n-乙酰胞壁質聚糖水解酶(n-acetylmuramideglycanohydralase)。
對于哺乳動物溶菌酶,其牛、豬、貓、兔、猴、馬、羊等動物的乳汁中分離出溶菌酶,其化學性質與人溶菌酶相似。
溶菌酶作為機體非特異免疫因子之一,參與機體多種免疫反應,在機體正常防御功能和非特異免疫中,具有保持機體生理平衡的重要作用。可改善和增強巨嗜細胞吞噬和消化功能,激活白細胞吞噬功能,并能改善細胞抑制劑所導致的白細胞減少,從而增強機體的抵抗力。
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