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Rabbit Anti-SLC25A6/APC Conjugated antibody (bs-7577R-APC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7577R-APC
英文名稱1 Rabbit Anti-SLC25A6/APC Conjugated antibody
中文名稱 APC標記的線粒體載體腺嘌呤核苷酸轉運蛋白6抗體
別    名 Adenine nucleotide translocator 3; ADP ATP carrier protein 3; ADP ATP carrier protein isoform T2; ADP ATP carrier protein liver; ADP/ATP translocase 3; ADP/ATP translocator of liver; ANT 3; ANT3; ANT3Y; MGC17525; Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 6; Solute carrier family 25 member 6; ADT3_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  轉錄調節因子  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Zebrafish, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC25A6 (65-100aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
SLC25A6 (solute carrier family 25, member A6) participates in the exchange of ADP and ATP across the mitochondrial inner membrane. It may be involved in the formation of the permeability transition pore complex (PTPC), a multiprotein complex built up at the contact site between the inner and the outer mitochondrial membranes. Opening of the PTPC causes massive swelling of mitochondria, rupture of the outer membrane and release of intermembrane components that induce apoptosis.

Function:
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

Subunit:
Found in a complex with ARL2, ARL2BP and SLC25A6. Homodimer. Interacts with influenza A virus PB1-F2 protein and HIV-1 Vpr.

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.

Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.

Database links:

Entrez Gene: 293 Human

Entrez Gene: 374072 Chicken

Entrez Gene: 282480 Cow

Entrez Gene: 67582 Mouse

Entrez Gene: 498885 Rat

Entrez Gene: 566370 Zebrafish

Omim: 300151 Human

Omim: 403000 Human

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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