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Rabbit Anti-Egr1/Gold Conjugated antibody (bs-1076R-Gold)
訂購(gòu)熱線(xiàn):400-901-9800
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-1076R-Gold
英文名稱(chēng)1 Rabbit Anti-Egr1/Gold Conjugated antibody
中文名稱(chēng) 膠體金標(biāo)記的早期生長(zhǎng)應(yīng)答蛋白1抗體
別    名 Egr-1; Early growth response 1; Krox-24; Ngf1; Ngfi; NGFI-A; zif-268; Egr1; A530045N19Rik; egr; Egr-1; ETR103; Krox-1; Krox-24; Krox24; NGF1-A; NGFI-A; NGFIA; TIS8; Zenk; Zfp-6; AT 225; AT225; Early growth response protein 1; G0S 30; G0S30; KROX 24; Krox 24 protein; KROX24; TIS 8; TIS8; Transcription factor ETR 103; Transcription factor ETR103; Transcription factor Zif 268; Transcription factor Zif268; Zfp 6; ZIF268; Zinc finger protein 225; ZNF 225; ZNF225; EGR1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Egr-1 (401-500aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. [provided by RefSeq].

Function:
Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the EGR C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.

Database links:

Entrez Gene: 1958 Human

Entrez Gene: 13653 Mouse

Omim: 128990 Human

SwissProt: P18146 Human

SwissProt: P08046 Mouse

Unigene: 326035 Human

Unigene: 708393 Human

Unigene: 181959 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Egr-1為即刻早期基因家族中的一個(gè)成員,是一種含3個(gè)鋅指結(jié)構(gòu)的轉(zhuǎn)錄因子。有研究表明EGR-1在細(xì)胞生長(zhǎng)分化中發(fā)揮重要作用,如在細(xì)胞周期G1-S期的轉(zhuǎn)換過(guò)程中Egr-1被誘導(dǎo)表達(dá)。
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