| 產(chǎn)品編號(hào) | bs-0736R-BF488 |
| 英文名稱1 | Rabbit Anti-CD56/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的神經(jīng)細(xì)胞粘附分子1抗體 |
| 別 名 | CD56 antigen; Cell Adhesion Molecule Neural 1; MSK39; N CAM 120; N CAM 140; N CAM 180; NCAM 1; NCAM 120; NCAM 140; NCAM1; Neural cell adhesion molecule 1 120 kDa isoform; Neural cell adhesion molecule 1 140 kDa isoform; Neural cell adhesion molecule 1; NCAM1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 干細(xì)胞 細(xì)胞類型標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, (predicted: Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 92kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD56/NCAM1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011] Function: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Subcellular Location: Isoform 1, 2,: Cell membrane; Single-pass type I membrane protein. Isoform 3, 4: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 5, 6: Secreted. Similarity: Contains 2 fibronectin type-III domains. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. Database links: Entrez Gene: 4684 Human Entrez Gene: 17967 Mouse Omim: 116930 Human SwissProt: P13591 Human SwissProt: P13595 Mouse Unigene: 503878 Human Unigene: 711235 Human Unigene: 733031 Human Unigene: 439182 Mouse Unigene: 4974 Mouse Unigene: 11283 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 細(xì)胞粘附蛋白（Call Adhesion Protein） 神經(jīng)元標(biāo)志物 NCAM-1為神經(jīng)細(xì)胞粘附分子，主要分布于神經(jīng)組織，神經(jīng)—肌肉接頭，神經(jīng)—內(nèi)分泌腺和某些內(nèi)分泌腺以及大多數(shù)神經(jīng)外胚層來源的細(xì)胞、組織和腫瘤中。 NCAM 1主要用于視網(wǎng)膜母細(xì)胞瘤、髓母細(xì)胞瘤、星形細(xì)胞瘤、神經(jīng)母細(xì)胞瘤等腫瘤方面的研究。CD56（神經(jīng)細(xì)胞黏附分子，NCAM）表達(dá)于大部分神經(jīng)外胚層來源的細(xì)胞系、組織和腫瘤如視網(wǎng)膜母細(xì)胞瘤、成神經(jīng)管細(xì)胞瘤、星形細(xì)胞瘤以及成神經(jīng)細(xì)胞瘤。它也表達(dá)于一些中胚層來源的腫瘤如橫紋肌肉瘤。NK細(xì)胞以及NK細(xì)胞淋巴瘤為陽性。CD56被認(rèn)為是NK細(xì)胞腫瘤的重要標(biāo)志物。該抗體識(shí)別分子量為180，145和125kDa亞型。 |
