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Rabbit Anti-NADPH/Cy7 Conjugated antibody (bs-1537R-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1537R-Cy7
英文名稱1 Rabbit Anti-NADPH/Cy7 Conjugated antibody
中文名稱 Cy7標記的還原型輔酶Ⅱ/磷酸酰胺腺嘌呤二核苷酸抗體
別    名 nicotinamide adenine dinucleotide phosphate; NADP; NADPH; TPNH; Triphosphopyridine nucleotide, reduced form;   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 小分子抗體 
研究領域 腫瘤  細胞生物  免疫學  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 0.833kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated NADPH
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
NDAPH (nicotinamide adenine dinucleotide phosphate) includes of Alpha-NADPH and Beta-NADPH. Beta-NADPH hase activity only. Beta-Nicotinamide adenine dinucleotide 2'-phosphate reduced tetrasodium salt or triphosphopyridine nucleotide reduced tetrasodium salt, also known as Coenzyme Ⅱ.
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

NADPH氧化酶廣泛存在于機體多個系統發揮重要的生理功能。在多種病理情況下,NADPH氧化酶可以在很多組織中催化合成大量活性氧,導致過度氧化應激,使組織細胞的功能下降。
NADPH氧化酶也是血管內皮細胞ROS產生的主要酶系,由其介導產生ROS在信息傳遞、基因轉錄、細胞生長和凋亡以及調節內皮依賴性的一氧化氮合酶脫偶聯等血管舒張中的作用,使其成為血管生物學中重要的部分,NADPH氧化酶一方面與血管舒張的機能異常有關,另一方面又影響到內皮細胞的結構、粘附分子的表達、滲透、成長及遷移等功能。
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