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Rabbit Anti-Desmoglein 3/Cy5 Conjugated antibody (bs-6585R-Cy5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6585R-Cy5
英文名稱1 Rabbit Anti-Desmoglein 3/Cy5 Conjugated antibody
中文名稱 Cy5標記的橋粒芯蛋白3抗體
別    名 130 kD pemphigus vulgaris antigen; Balding; CDHF 6; CDHF6; Desmoglein 3 precursor; Desmoglein3; DKFZp686P23184; DSG 3; DSG3; DSG-3; Pemphigus vulgaris antigen; PVA; DSG3_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 信號轉導  細胞粘附分子  細胞骨架  細胞外基質  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 105kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Desmoglein 3 (50-75aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.

Tissue Specificity:
Epidermis, tongue, tonsil, esophagus and carcinomas.

Similarity:
Contains 4 cadherin domains.

Database links:
 

UniProtKB/Swiss-Prot: P32926.2



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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