| 產品編號 |
bsk11085 |
| 英文名稱 |
Human MCP-2/CCL8 ELISA Kit
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| 中文名稱 |
人單核細胞趨化蛋白2酶聯免疫試劑盒 |
| 別 名 |
CCL8, HC14, MCP-2, MCP2, SCYA10, SCYA8, C-C motif chemokine ligand 8 |
| 種 屬 |
Human |
| 線性范圍 |
1.56 - 100 pg/mL |
| 應用范圍 |
S/P/CC |
| 檢測限 |
0.8 pg/mL |
| 適用樣品基質 |
cell culture supernates, serum, and plasma. |
| 保存條件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 |
Chemokine (C-C motif) ligand 8 (CCL8), also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene.CCL8 is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans.MCP-2 is chemotactic for and activates a many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response.CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B and CCR5.
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