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Mouse Anti-FGFR1OP2  antibody (bsm-51372M)  
~~~促銷(xiāo)代碼KT202411~~~
訂購(gòu)熱線:400-901-9800
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說(shuō)明書(shū): 50ul  100ul  
50ul/1580.00元
100ul/2500.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bsm-51372M
英文名稱(chēng) Mouse Anti-FGFR1OP2  antibody
中文名稱(chēng) FGFR1癌基因伴侶蛋白2單克隆抗體
別    名 DKFZp564O1863; FGFR1 oncogene partner 2; HSPC123; HSPC123 like; FGOP2_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  激酶和磷酸酶  
抗體來(lái)源 Mouse
克隆類(lèi)型 Monoclonal
克 隆 號(hào) 11B8
交叉反應(yīng) (predicted: Human,Mouse)
產(chǎn)品應(yīng)用 WB=1:1000-5000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FGFR1OP2 
亞    型 IgG2a
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 FGFR1OP2 belongs to the SIKE family. The FGFR1OP2 (FGFR1 oncogene partner 2) gene was identified through its involvement in a fusion with the FGFR1 gene. FGFR1OP2 may be involved in the wound healing pathway. It is expressed in bone marrow, spleen and thymus. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T cell or B cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.

Function:
May be involved in wound healing pathway (By similarity).

Subcellular Location:
Cytoplasm (By similarity).

Tissue Specificity:
Expressed in bone marrow, spleen and thymus.

DISEASE:
Note=A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.

Similarity:
Belongs to the SIKE family.

SWISS:
Q9NVK5

Gene ID:
26127

Database links:

Entrez Gene: 26127 Human

Entrez Gene: 67529 Mouse

Entrez Gene: 362463 Rat

Omim: 608858 Human

SwissProt: Q9NVK5 Human

SwissProt: Q9CRA9 Mouse

SwissProt: Q6TA25 Rat

Unigene: 591162 Human

Unigene: 333499 Mouse

Unigene: 68658 Rat



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