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Rabbit Anti-MTCH1  antibody (bs-23546R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-23546R
英文名稱 Rabbit Anti-MTCH1  antibody
中文名稱 線粒體載體同源物1抗體
別    名 Cell proliferation inducing protein 60; CGI-64; CGI64; Mitochondrial carrier homolog 1; Mitocondrial Carrier Homolog 1; MTCH 1; MTCH1_HUMAN; Presenilin Associated Protein; Presenilin-associated protein; PSAP.  
研究領域 細胞生物  神經生物學  信號轉導  細胞凋亡  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Pig,GuineaPig)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42kDa
細胞定位 細胞漿 細胞膜 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MTCH1: 1-100/389 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]

Function:
Potential mitochondrial transporter. May play a role in apoptosis.

Subunit:
Interacts with PSEN1.

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:
Widely expressed with a predominant expression in brain.

Similarity:
Belongs to the mitochondrial carrier family.
Contains 2 Solcar repeats.

SWISS:
Q9NZJ7

Gene ID:
23787

Database links:

Entrez Gene: 23787 Human

Omim: 610449 Human

SwissProt: Q9NZJ7 Human

Unigene: 485262 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MTCH1) Polyclonal Antibody, Unconjugated (bs-23546R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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