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Mouse Anti-RAB18  antibody (bsm-51333M)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  
50ul/1580.00元
100ul/2500.00元
大包裝/詢價
產品編號 bsm-51333M
英文名稱 Mouse Anti-RAB18  antibody
中文名稱 G蛋白家族RAB18蛋白單克隆抗體
別    名 RAB18; RAB18 member RAS oncogene family; RAB18 small GTPase; RAB18_HUMAN; RAB18LI1; Ras-related protein Rab-18.  
研究領域 細胞生物  信號轉導  轉錄調節因子  G蛋白信號  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 3A8
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 23kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human RAB18 protein 
亞    型 IgG1
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
Q9NP72

Gene ID:
22931

Database links:

Entrez Gene: 22931 Human

Entrez Gene: 19330 Mouse

Entrez Gene: 307039 Rat

Omim: 602207 Human

SwissProt: Q9NP72 Human

SwissProt: P35293 Mouse

SwissProt: Q5EB77 Rat

Unigene: 406799 Human

Unigene: 132802 Mouse

Unigene: 472772 Mouse

Unigene: 53248 Rat



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