產(chǎn)品編號 | bs-21285R |
英文名稱 | Rabbit Anti-RBM11 antibody |
中文名稱 | RNA結(jié)合蛋白11抗體 |
別 名 | Putative RNA binding protein 11; RNA binding motif protein 11; Splicing regulator RBM11; RBM11_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 結(jié)合蛋白 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 32kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RBM11: 131-230/281 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
RBM11, also known as RNA binding motif protein 11, is a human gene. 2 isoforms of the human protein are produced by alternative splicing. Function: Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1. Subunit: Homodimer. Subcellular Location: Nucleus. Tissue Specificity: Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain. Similarity: Contains 1 RRM (RNA recognition motif) domain. SWISS: P57052 Gene ID: 54033 Database links: Entrez Gene: 54033 Human SwissProt: P57052 Human Unigene: 283828 Human Unigene: 154372 Rat |