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Rabbit Anti-RALGPS1  antibody (bs-21147R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產(chǎn)品編號 bs-21147R
英文名稱 Rabbit Anti-RALGPS1  antibody
中文名稱 RALGPS1蛋白抗體
別    名 Ral GEF with PH domain and SH3 binding motif 1; RalA exchange factor RalGPS1; RALGEF2; RALGPS1A; Ras specific guanine nucleotide releasing factor RalGPS1.  
研究領域 細胞生物  信號轉(zhuǎn)導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 62kDa
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RALGPS1: 461-557/557 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 May be involved in cytoskeletal organization (By similarity). May also be involved in the stimulation of transcription in a Ras independent fashion (By similarity). Guanine nucleotide exchange factor for the small GTPase RALA. Six different isoforms have been described.

Function:
Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for.

Subunit:
Interacts with the SH3 domains of GRB2, NCK1, PLCG1 and SRC.

Subcellular Location:
Cell Membrane and Cytoplasmic.

Tissue Specificity:
Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus.

SWISS:
Q5JS13

Gene ID:
9649

Database links:

Entrez Gene: 9649 Human

SwissProt: Q5JS13 Human

Unigene: 648175 Human



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