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Rabbit Anti-RBMY1A1  antibody (bs-10923R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-10923R
英文名稱 Rabbit Anti-RBMY1A1  antibody
中文名稱 RNA結合蛋白片段Y染色體家族蛋白1抗體
別    名 hRBMY; MGC181956; RBM1; RBM2; RBMY; RNA binding motif protein 1; RNA binding motif protein 2; RNA binding motif protein Y chromosome family 1 member A1; RNA binding motif protein Y chromosome family 1 member A1/C; RNA binding motif protein Y chromosome family 1 member; RNA binding motif protein Y linked family 1 member A1; Y chromosome RNA recognition motif 1; YRRM1; YRRM2; RBY1A_HUMAN.  
研究領域 發育生物學  干細胞  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBMY1A1: 81-180/496 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq, Jul 2008]

Function:
RBMY1A1 is an RNA-binding protein which may be involved in spermatogenesis. It is required for sperm development, possibly by participating in pre-mRNA splicing in the testis.

Subunit:
Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3.

Subcellular Location:
Nuclear.

Tissue Specificity:
Testis-specific.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
P0DJD3

Gene ID:
5940

Database links:

Entrez Gene: 5940 Human

Omim: 400006 Human

SwissProt: P0DJD3 Human

Unigene: 380450 Human



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