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Rabbit Anti-ZNF189  antibody (bs-7177R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-7177R
英文名稱 Rabbit Anti-ZNF189  antibody
中文名稱 鋅指蛋白189抗體
別    名 Zinc finger protein 189; ZN189_HUMAN; ZNF189.  
研究領域 鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Cow)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 73kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF189: 401-500/626 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Kruppel-like zinc finger proteins such as ZNF189 contain a conserved stretch of 7 amino acids that connects a variable number of DNA-binding zinc finger repeats of the cys(2)his(2) (C2H2) type (summarized by Odeberg et al., 1998 [PubMed 9653648]). Approximately 30% of human Kruppel-like zinc finger proteins contain an N-terminal Kruppel-associated box (KRAB) domain. The KRAB domain consists of approximately 75 amino acids that may be subdivided into an A box, which is present in every KRAB domain and is essential for transcriptional repression, and a B box, which is not always present.[supplied by OMIM, May 2010]

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 16 C2H2-type zinc fingers.
Contains 1 KRAB domain.

SWISS:
O75820

Gene ID:
7743

Database links:

Entrez Gene: 540816 Cow

Entrez Gene: 7743 Human

Omim: 603132 Human

SwissProt: O75820 Human

Unigene: 50123 Human



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