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Rabbit Anti-Surb7  antibody (bs-12845R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-12845R
英文名稱 Rabbit Anti-Surb7  antibody
中文名稱 Surb7蛋白抗體
別    名 MED21; hSrb7; MED21; MED21_HUMAN; Mediator complex subunit 21; Mediator of RNA polymerase II transcription subunit 21; RNA polymerase II holoenzyme component SRB7; RNAPII complex component SRB7; SRB7; SRB7 suppressor of RNA polymerase B homolog; Surb7.  
研究領域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Sheep,Cow,Dog)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 15kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Surb7: 1-100/144 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Mediator complex subunit 21 family.

SWISS:
Q13503

Gene ID:
9412

Database links:

Entrez Gene: 418216 Chicken

Entrez Gene: 539496 Cow

Entrez Gene: 9412 Human

Entrez Gene: 108098 Mouse

Entrez Gene: 312849 Rat

Entrez Gene: 406732 Zebrafish

Omim: 603800 Human

SwissProt: Q2TBU8 Cow

SwissProt: Q13503 Human

SwissProt: Q9CQ39 Mouse

SwissProt: Q7ZTI5 Zebrafish

Unigene: 286145 Human

Unigene: 26212 Mouse

Unigene: 81879 Zebrafish



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