| 產(chǎn)品編號 | bs-12632R |
| 英文名稱 | Rabbit Anti-PFKFB4 antibody |
| 中文名稱 | 果糖-2,6-二磷酸酶4抗體 |
| 別 名 | 6-bisphosphatase; 6-P2ase 4; 6-P2ASE testis-type isozyme; 6-phosphofructo-2-kinase; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4; 6PF 2 K/Fru 2,6 P2ase 4; 6PF 2 K/Fru 2,6 P2ase testis type isozyme; 6PF-2-K/Fru-2; 6PF-2-K/Fru-2,6-P2ase; Bifunctional enzyme with kinase and biphosphatase activities; F264_HUMAN; Fructose-2; Fructose-2,6-bisphosphatase; PFK/FBPase 4; PFKFB4. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 54kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PFKFB4: 2-100/469 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] Function: Synthesis and degradation of fructose 2,6-bisphosphate. Subunit: Homodimer. Similarity: In the C-terminal section; belongs to the phosphoglycerate mutase family. SWISS: Q16877 Gene ID: 5210 Database links: Entrez Gene: 5210 Human Entrez Gene: 270198 Mouse Omim: 605320 Human SwissProt: Q16877 Human SwissProt: Q6DTY7 Mouse Unigene: 476217 Human Unigene: 249861 Mouse Unigene: 90092 Rat |
