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Rabbit Anti-PPFIA4  antibody (bs-21056R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-21056R
英文名稱 Rabbit Anti-PPFIA4  antibody
中文名稱 酪氨酸磷酸酶受體相互作用蛋白Liprin α4抗體
別    名 KIAA0897; LIPA4_HUMAN; Liprin alpha 4; Liprin-alpha-4; PPFIA 4; PPFIA4; Protein tyrosine phosphatase receptor type f polypeptide (PTPRF) interacting protein (liprin) alpha 4; Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 4; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4; PTPRF interacting protein alpha 4; PTPRF-interacting protein alpha-4.  
研究領域 細胞生物  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PPFIA4: 1001-1100/1185 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 PPFIA4, or liprin-alpha-4, belongs to the liprin-alpha gene family. See liprin-alpha-1 (LIP1, or PPFIA1; MIM 611054) for background on liprins.[supplied by OMIM, Mar 2008]

Function:
May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.

Subcellular Location:
Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.

Tissue Specificity:
Expressed only in the heart, brain, and skeletal muscle.

Similarity:
Belongs to the liprin family. Liprin-alpha subfamily.
Contains 3 SAM (sterile alpha motif) domains.

SWISS:
O75335

Gene ID:
8497

Database links:

Entrez Gene: 8497 Human

Entrez Gene: 68507 Mouse

Entrez Gene: 140592 Rat

Omim: 603145 Human

SwissProt: O75335 Human

SwissProt: Q91Z80 Rat

Unigene: 153648 Human

Unigene: 105913 Rat



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