產品編號 | bs-19991R |
英文名稱 | Rabbit Anti-PPP1R1C antibody |
中文名稱 | 蛋白磷酸酶1調節亞基1c抗體 |
別 名 | Inhibitor 5 of protein phosphatase 1; IPP5; PP1 inhibitor protein 5; Ppp1r1c; PPR1C_HUMAN; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase 1 regulatory subunit 1C; protein phosphatase 1, regulatory (inhibitor) subunit 1C. |
研究領域 | 細胞生物 神經生物學 信號轉導 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Dog) |
產品應用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 12kDa |
細胞定位 | 細胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PPP1R1C: 1-100/567 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產品介紹 |
This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] Function: Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons. Subcellular Location: Cytoplasm. Tissue Specificity: Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level). Post-translational modifications: Phosphorylation at Ser-56 favors interaction with CALM1. Isoform 1 is methylated by CARM1 in immature thymocytes. Similarity: Contains 1 R3H domain. SWISS: Q8WVI7 Gene ID: 151242 Database links: Entrez Gene: 10777 Human Entrez Gene: 74100 Mouse Omim: 605488 Human SwissProt: Q9UBL0 Human SwissProt: Q9DCB4 Mouse Unigene: 475902 Human Unigene: 713605 Human Unigene: 297444 Mouse |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |