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Rabbit Anti-RGS8  antibody (bs-19864R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-19864R
英文名稱 Rabbit Anti-RGS8  antibody
中文名稱 G蛋白信號轉導調節因子8抗體
別    名 Regulator of G Protein Signalling 8; Regulator of G-protein signaling 8; RGS8; RGS8_HUMAN.  
研究領域 細胞生物  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Cow)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 21kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RGS8: 1-100/180 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008]

Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Preferentially binds to G(o)-alpha and G(i)-alpha-3.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 RGS domain.

SWISS:
P57771

Gene ID:
85397

Database links:

Entrez Gene: 85397 Human

Entrez Gene: 67792 Mouse

Entrez Gene: 54297 Rat

Omim: 607189 Human

SwissProt: P57771 Human

SwissProt: Q8BXT1 Mouse

SwissProt: P49804 Rat

Unigene: 20982 Human

Unigene: 458417 Human

Unigene: 379143 Mouse

Unigene: 89634 Rat



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