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Rabbit Anti-SH2D1B  antibody (bs-19744R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
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產品編號 bs-19744R
英文名稱 Rabbit Anti-SH2D1B  antibody
中文名稱 EAT2蛋白抗體
別    名 EAT 2; EAT2; EWS/FLI1 activated transcript 2; SH2 domain containing 1B; SH2 domain containing molecule EAT2; SH2 domain containing protein 1B.  
研究領域 細胞生物  細胞膜受體  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 15kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SH2D1B: 21-100/132 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008]

Function:
Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells.

Subunit:
Binds to the phosphorylated receptors CD84, SLAMF1, LY9 and CD244. Does not bind to non-phosphorylated SLAMF1.

Similarity:
Contains 1 SH2 domain.

SWISS:
O14796

Gene ID:
117157

Database links:

Entrez Gene: 117157 Human

SwissProt: O14796 Human

Unigene: 350581 Human



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