產(chǎn)品編號(hào) | bs-10927R |
英文名稱 | Rabbit Anti-Aquaporin 5 antibody |
中文名稱 | 水通道蛋白5抗體 |
別 名 | Aquaporin 5; AQP5; AQP 5; AQP-5; AQP5_HUMAN; Aquaporin-5. |
Specific References (2) | bs-10927R has been referenced in 2 publications.
[IF=3.266] Dai TQ et al. In vitro transdifferentiation of adipose tissue-derived stem cells into salivary gland acinar-like cells. Am J Transl Res. 2019 May 15;11(5):2908-2924. ICF&WB ; Mouse.
[IF=2.027] Ba F et al. Lipoxin A4 ameliorates alveolar fluid clearance disturbance in lipopolysaccharide-induced lung injury via aquaporin 5 and MAPK signaling pathway. J Thorac Dis 2019;11(8):3599-3608 WB ; Mouse.
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研究領(lǐng)域 | 信號(hào)轉(zhuǎn)導(dǎo) 通道蛋白 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse,Rat (predicted: Pig) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 29kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Aquaporin 5: 151-250/265 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008] Function: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family. SWISS: P55064 Gene ID: 362 Database links:
Entrez Gene: 362 Human
Entrez Gene: 11830 Mouse
Omim: 600442 Human
SwissProt: P55064 Human
SwissProt: Q9WTY4 Mouse
Unigene: 298023 Human
Unigene: 45580 Mouse
Unigene: 10066 Rat
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產(chǎn)品圖片 |
Sample:
Eye (Rat) Lysate at 40 ug
Primary: Anti-Aquaporin 5 (bs-10927R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kD
Observed band size: 29 kD
Tissue/cell: human laryngocarcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Aquaporin Polyclonal Antibody, Unconjugated(bs-10927R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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